别名PRO285; TLR 7; Tlr7; Toll like receptor 7; UNQ248;
应用WB;IHC
反应物种Human
理论分子量121 kDa
表观分子量140 kDa
免疫原A synthetic peptide of human TLR7
基因ID51284
蛋白编码Q9NYK1
宿主物种Rabbit
抗体分型IgG
纯化Affinity purification
储存Store at -20℃. Avoid freeze / thaw cycles.
靶点背景The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung, placenta, and spleen, and lies in close proximity to another family member, TLR8, on chromosome X.
推荐稀释比WB 1:1000-1:2000 IHC 1:100-1:200
产品形式Liquid
Buffer 体系PBS with 1% BSA, 0.03% Proclin300 and 50% Glycerol.