别名CENP E; Centromere associated protein E; Centromere protein E 312kDa; KIF10; Kinesin family member 10; Kinesin related protein; PPP1R61;
应用WB
反应物种Human
理论分子量316 kDa
表观分子量312 kDa
免疫原A synthetic peptide of human CENPE
基因ID1062
蛋白编码Q02224
宿主物种Rabbit
抗体分型IgG
纯化Affinity purification
储存Store at -20℃. Avoid freeze / thaw cycles.
靶点背景Centrosome-associated protein E (CENPE) is a kinesin-like motor protein that accumulates in the G2 phase of the cell cycle. Unlike other centrosome-associated proteins, it is not present during interphase and first appears at the centromere region of chromosomes during prometaphase. This protein is required for stable spindle microtubule capture at kinetochores which is a necessary step in chromosome alignment during prometaphase. This protein also couples chromosome position to microtubule depolymerizing activity. Alternative splicing results in multiple transcript variants encoding distinct protein isoforms.
推荐稀释比WB 1:1000-1:2000
产品形式Liquid
Buffer 体系PBS with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
