![JP31069 [KO Validated] EIF4EBP1 Polyclonal Antibody](../include/thumb.php?dir=../upload/202204/1649749122.jpg&x=400&y=300)
![JP31069 [KO Validated] EIF4EBP1 Polyclonal Antibody](../include/thumb.php?dir=../upload/202204/1649749122.jpg&x=60&y=60)
Product Information： | |
Product name | [KO Validated] EIF4EBP1 Polyclonal Antibody |
Isotype | IgG |
Form | Lyophilized or Liquid |
Tested applications | WB,IHC,IF,ELISA |
Species reactivity | Human,Mouse,Rat |
Host Species | Rabbit |
Purity | Affinity purification |
Immunogen Information：
Immunogen | A synthetic peptide corresponding to a sequence within amino acids 50 to the C-terminus of human EIF4EBP1 |
Calculated molecular weight | 12kDa |
Observed molecular weight | 20kDa, 22kDa |
Swiss Prot | Q13541 |
Gene ID (NCBI) | 1978 |
Alternative Names | 4E-BP1;4EBP1;BP-1;PHAS-I;EIF4EBP1 |
Application Notes：
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB | 1:500 - 1:1000 |
IHC | 1:50 - 1:200 |
IF | 1:100 - 1:200 |
Background：
This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.
Storage：
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Services & Support：
1. Please do not hesitate to contact us if you have any questions.
2. Please fill in the Technical Suppoprt Request Form and email the form to jiyinmei027@163.com within 3 months of receipt of the goods, and we will response to your inquiry within 24 hours.
The after-sale service channel will be shut down after 3 months.
