Product Information： | |
Product name | HR Polyclonal Antibody |
Isotype | IgG |
Form | Lyophilized or Liquid |
Tested applications | WB,ELISA |
Species reactivity | Human,Mouse,Rat |
Host Species | Rabbit |
Purity | Affinity purification |
Immunogen Information：
Immunogen | Recombinant protein of human HR |
Calculated molecular weight | 121kDa/127kDa |
Observed molecular weight | 120kDa |
Swiss Prot | O43593 |
Gene ID (NCBI) | 55806 |
Alternative Names | ALUNC;AU;HSA277165;HYPT4;MUHH;MUHH1 |
Application Notes：
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB | 1:500 - 1:1000 |
Background：
This gene encodes a protein that is involved in hair growth. This protein functions as a transcriptional corepressor of multiple nuclear receptors, including thyroid hormone receptor, the retinoic acid receptor-related orphan receptors and the vitamin D receptors, and it interacts with histone deacetylases. The translation of this protein is modulated by a regulatory open reading frame (ORF) that exists upstream of the primary ORF. Mutations in this upstream ORF cause Marie Unna hereditary hypotrichosis (MUHH), an autosomal dominant form of genetic hair loss. Mutations in this gene also cause autosomal recessive congenital alopecia and atrichia with papular lesions, other diseases resulting in hair loss. Two transcript variants encoding different isoforms have been found for this gene.
Storage：
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Services & Support：
1. Please do not hesitate to contact us if you have any questions.
2. Please fill in the Technical Suppoprt Request Form and email the form to jiyinmei027@163.com within 3 months of receipt of the goods, and we will response to your inquiry within 24 hours.
3. The after-sale service channel will be shut down after 3 months.
