Product Information： | |
Product name | IDH2 Polyclonal Antibody |
Isotype | IgG |
Form | Lyophilized or Liquid |
Tested applications | WB,IHC,IF,ELISA |
Species reactivity | Human,Mouse,Rat |
Host Species | Rabbit |
Purity | Affinity purification |
Immunogen Information：
Immunogen | Recombinant protein of human IDH2 |
Calculated molecular weight | 45kDa/50kDa |
Observed molecular weight | 51kDa |
Swiss Prot | P48735 |
Gene ID (NCBI) | 3418 |
Alternative Names | D2HGA2;ICD-M;IDH;IDHM;IDP;IDPM;mNADP-IDH |
Application Notes：
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB | 1:500 - 1:2000 |
IHC | 1:50 - 1:200 |
IF | 1:20 - 1:50 |
Background：
Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex. Alternative splicing results in multiple transcript variants.
Storage：
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Services & Support：
1. Please do not hesitate to contact us if you have any questions.
2. Please fill in the Technical Suppoprt Request Form and email the form to jiyinmei027@163.com within 3 months of receipt of the goods, and we will response to your inquiry within 24 hours.
3. The after-sale service channel will be shut down after 3 months.
