别名A5 protein; BDCA4; CD304 ; Neuropilin1; NP1; NPN1; NRP1; VEGF165R ; NEL like protein 1; Blood dendritic cell antigen 4 ;
应用WB;IHC;ICC/IF;IHF;IP;FC
反应物种Human;Mouse;Rat
理论分子量103 kDa
表观分子量120 kDa
免疫原A synthetic peptide of human Neuropilin 1
基因ID8829
蛋白编码O14786
宿主物种Rabbit
抗体分型IgG
纯化Affinity purification
储存Store at -20℃. Avoid freeze / thaw cycles.
靶点背景This gene encodes one of two neuropilins, which contain specific protein domains which allow them to participate in several different types of signaling pathways that control cell migration. Neuropilins contain a large N-terminal extracellular domain, made up of complement-binding, coagulation factor V/VIII, and meprin domains. These proteins also contains a short membrane-spanning domain and a small cytoplasmic domain. Neuropilins bind many ligands and various types of co-receptors; they affect cell survival, migration, and attraction. Some of the ligands and co-receptors bound by neuropilins are vascular endothelial growth factor (VEGF) and semaphorin family members. Several alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.
推荐稀释比WB 1:1000-1:2000 IHC 1:100-1:200 ICC/IF 1:50-1:200 IHF 1:50-1:200 IP 1:20-1:50 FC 1:20-1:100
产品形式Liquid
Buffer 体系PBS with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
