别名ACO 1; Aconitase; Citrate hydro lyase; IREB1; IRP 1; Iron responsive element binding protein 1;
应用WB;ICC/IF
反应物种Human;Mouse;Rat
理论分子量98 kDa
表观分子量98 kDa
免疫原A synthetic peptide of human ACO1
基因ID48
蛋白编码P21399
宿主物种Rabbit
抗体分型IgG
纯化Affinity purification
储存Store at -20℃. Avoid freeze / thaw cycles.
靶点背景Iron sensor. Binds a 4Fe-4S cluster and functions as aconitase when cellular iron levels are high. Functions as mRNA binding protein that regulates uptake, sequestration and utilization of iron when cellular iron levels are low. Binds to iron-responsive elements (IRES) in target mRNA species when iron levels are low. Binding of a 4Fe-4S cluster precludes RNA binding. Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.
推荐稀释比WB 1:1000-1:2000 ICC/IF 1:50-1:200
产品形式Liquid
Buffer 体系PBS with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
