别名Keratin, type I cytoskeletal 13; Krt1-13; Cytokeratin 13; CK13; Keratin 13; KRT13; WSN2;
应用WB;IHC;ICC/IF;IHF
反应物种Human;Mouse
理论分子量50 kDa
表观分子量50 kDa
免疫原A synthetic peptide of human KRT13
基因ID3860
蛋白编码P13646
宿主物种Rabbit
抗体分型IgG
纯化Affinity purification
储存Store at -20℃. Avoid freeze / thaw cycles.
靶点背景The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This type I cytokeratin is paired with keratin 4 and expressed in the suprabasal layers of non-cornified stratified epithelia. Mutations in this gene and keratin 4 have been associated with the autosomal dominant disorder White Sponge Nevus. The type I cytokeratins are clustered in a region of chromosome 17q21.2. Alternative splicing of this gene results in multiple transcript variants; however, not all variants have been described.
