别名DNA repair protein XRCC1; RCC; X ray repair complementing defective repair in chinese hamster; XRCC 1;
应用WB;IHC;ICC/IF;IHF
反应物种Human;Mouse;Rat
理论分子量69 kDa
表观分子量90 kDa
免疫原A synthetic peptide of human XRCC1
基因ID7515
蛋白编码P18887
宿主物种Rabbit
抗体分型IgG
纯化Affinity purification
储存Store at -20℃. Avoid freeze / thaw cycles.
靶点背景The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.
