别名CSDD2; FLJ16517; LIN28B; Protein lin-28 homolog B;
应用WB,IF-ICC,FCM,IP
反应物种Human
理论分子量32kDa
表观分子量27kDa
免疫原A synthetic peptide of human LIN28B
基因ID389421
蛋白编码Q6ZN17
宿主物种Rabbit
抗体分型IgG
纯化Affinity purification
储存Store at -20℃. Avoid freeze / thaw cycles.
靶点背景The protein encoded by this gene belongs to the lin-28 family, which is characterized by the presence of a cold-shock domain and a pair of CCHC zinc finger domains. This gene is highly expressed in testis, fetal liver, placenta, and in primary human tumors and cancer cell lines. It is negatively regulated by microRNAs that target sites in the 3' UTR, and overexpression of this gene in primary tumors is linked to the repression of let-7 family of microRNAs and derepression of let-7 targets, which facilitates cellular transformation.
推荐稀释比WB 1:1000 IF-ICC 1:200 FCM 1:20 IP 1:20
产品形式Liquid
Buffer 体系PBS with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
