别名TGF-beta receptor type-2; TGFR-2; TGFR2; TGF-beta type II receptor; TbetaR-II; TGFBR2;
应用WB,IHC-P,IF-P,IF-F,IF-ICC,IP,ELISA
反应物种Human,Mouse,Rat
理论分子量65kDa
表观分子量65kDa
免疫原A synthetic peptide of human TGFBR2
基因ID7048
蛋白编码P37173
宿主物种Rabbit
抗体分型IgG
纯化Affinity purification
储存Store at -20℃. Avoid freeze / thaw cycles.
靶点背景This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized.
推荐稀释比WB 1:1000-1:5000 IHC-P 1:200-1:500 IF-P/IF-F/IF-ICC 1:200-1:1000 IP 1:50-1:200 ELISA 1:5000-1:20000
产品形式Liquid
Buffer 体系PBS with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
