别名Antithrombin; Antithrombin III; AT 3; AT III; AT3; AT3D; ATIII; Heparin cofactor I; Serpin C1; Serpin family C member 1; SERPINC1; THPH7;
应用WB
反应物种Human,Mouse,Rat
理论分子量53kDa
表观分子量53kDa
免疫原A synthetic peptide of human SERPINC1
基因ID462
蛋白编码P01008
宿主物种Rabbit
抗体分型IgG
纯化Affinity purification
储存Store at -20℃. Avoid freeze / thaw cycles.
靶点背景The protein encoded by this gene is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency.
推荐稀释比WB 1:1000-1:5000
产品形式Liquid
Buffer 体系PBS with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
