别名AG1; AGR1; ER protein 18; ER protein 19; ERP 18; ERP16; ERP19; hAG1; hTLP19; PDIA16; TLP19; TXNDC12;
应用WB,IHC-P,IF-ICC
反应物种Human,Mouse,Rat
理论分子量19kDa
表观分子量19kDa
免疫原A synthetic peptide of human TXNDC12
基因ID51060
蛋白编码O95881
宿主物种Rabbit
抗体分型IgG
纯化Affinity purification
储存Store at -20℃. Avoid freeze / thaw cycles.
靶点背景TXNDC12, which is known as thioredoxin domain-containing protein 12, ERp16, ERp18, ERp19, or hTLP19, is a member of the protein disulfide isomerase (PDI) family that plays important roles in cancer development and progression. TXNDC12 has been demonstrated to contribute to tumorigenicity in human gastric cancer by promoting cell growth, migration and invasion(PMID: 25940440). Other study also revealed the overexpression of TXNDC12 promotes HCC metastasis through β-catenin-mediated induction of EMT and that TXNDC12 has the potential to be a prognostic factor and therapeutic target of HCC.(PMID: 31570854)
