产品名称Phospho-eIF4EBP1/eIF4EBP2/eIF4EBP3 (Thr45) Rabbit mAb
别名BP-1; 4EBP1; 4E-BP1; PHAS-I
应用WB,IHC-P
反应物种Human,Mouse
理论分子量15-20kDa
表观分子量13kDa
免疫原A synthetic phosphopeptide corresponding to residues surrounding
Thr45 of human eIF4EBP1
基因ID1978
蛋白编码Q13541
宿主物种Rabbit
抗体分型IgG
纯化Affinity purification
储存Store at -20℃. Avoid freeze / thaw cycles.
靶点背景This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. [provided by RefSeq, Jul 2008]
推荐稀释比WB 1:1000-1:5000 IHC-P/IF-P 1:50-1:100
产品形式Liquid
Buffer 体系PBS with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
