靶点背景GRM2, also named as GPRC1B and MGLUR2, belongs to the G-protein coupled receptor 3 family. GRM2 is a receptor for glutamate. The activity of GRM2 is mediated by a G-protein that inhibits adenylate cyclase activity. It may mediate suppression of neurotransmission or may be involved in synaptogenesis or synaptic stabilization.
