同义词SLEB1; TIL3; Tlr5; Toll like receptor 5 precursor;
宿主物种Rabbit
抗体分型IgG
纯化Affinity purification
储存Store at -20℃. Avoid freeze / thaw cycles.
靶点背景This gene encodes a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct pathogen-associated molecular patterns that are expressed on infectious agents. The protein encoded by this gene recognizes bacterial flagellin, the principal component of bacterial flagella and a virulence factor. The activation of this receptor mobilizes the nuclear factor NF-kappaB, which in turn activates a host of inflammatory-related target genes. Mutations in this gene have been associated with both resistance and susceptibility to systemic lupus erythematosus, and susceptibility to Legionnaire disease.
推荐稀释比WB 1:1000-1:2000 ICC/IF 1:50-1:200
产品形式Liquid
Buffer 体系PBS with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
