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基因美电话027-88411411
Rabbit Monoclonal Antibody
兔单克隆抗体
APOC3 Rabbit mAb

货号:R06141

  • 规格价格
  • 100 μL 1800
  • 50 μL 1000
货期:
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  • 应用WB,IHC-P,IF-P
  • 反应物种Human
  • 理论分子量11kDa
  • 表观分子量11kDa
  • 免疫原A synthetic peptide of human APOC3
  • 基因ID345
  • 蛋白编码P02656
  • 同义词APOC3; APO C3; Apo CIII; ApoC III; APOC3; ApoCIII; Apolipoprotein C III; Apolipoprotein C3;
  • 宿主物种Rabbit
  • 抗体分型IgG
  • 纯化Affinity purification
  • 储存Store at -20℃. Avoid freeze / thaw cycles.
  • 靶点背景Component of triglyceride-rich very low density lipoproteins (VLDL) and high density lipoproteins (HDL) in plasma (PubMed:18201179, PubMed:22510806). Plays a multifaceted role in triglyceride homeostasis (PubMed:18201179, PubMed:22510806). Intracellularly, promotes hepatic very low density lipoprotein 1 (VLDL1) assembly and secretion; extracellularly, attenuates hydrolysis and clearance of triglyceride- rich lipoproteins (TRLs) (PubMed:18201179, PubMed:22510806). Impairs the lipolysis of TRLs by inhibiting lipoprotein lipase and the hepatic uptake of TRLs by remnant receptors (PubMed:18201179, PubMed:22510806). Formed of several curved helices connected via semiflexible hinges, so that it can wrap tightly around the curved micelle surface and easily adapt to the different diameters of its natural binding partners (PubMed:18408013).
  • 推荐稀释比WB 1:1000
    IHC-P/IF-P 1:50
  • 产品形式Liquid
  • Buffer 体系PBS with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
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