免疫原Full length human recombinant protein of human IFT57(NP_060480) produced in HEK293T cell.
基因ID73916 (Mouse);303968 (Rat);55081 (Human);
蛋白编码Q9NWB7
同义词ESRRBL1; HIPPI; MHS4R2
宿主物种Mouse
抗体分型IgG1
纯化Affinity purification
储存Store at -20℃. Avoid freeze / thaw cycles.
靶点背景HIPPI is required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway. Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator; however the relevance of such function remains unclear.
推荐稀释比WB 1:2000< br/>IHC 1:50< br/>IF 1:100
产品形式Liquid
Buffer 体系PBS with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
