免疫原Full length human recombinant protein of human SHPK(NP_037408) produced in HEK293T cell.
基因ID74637 (Mouse);287479 (Rat);23729 (Human);
蛋白编码Q9UHJ6
同义词CARKL; SHK
宿主物种Mouse
抗体分型IgG1
纯化Affinity purification
储存Store at -20℃. Avoid freeze / thaw cycles.
靶点背景The protein encoded by this gene has weak homology to several carbohydrate kinases, a class of proteins involved in the phosphorylation of sugars as they enter a cell, inhibiting return across the cell membrane. Sequence variation between this novel gene and known carbohydrate kinases suggests the possibility of a different substrate, cofactor or changes in kinetic properties distinguishing it from other carbohydrate kinases. The gene resides in a region commonly deleted in cystinosis patients, suggesting a role as a modifier for the cystinosis phenotype. The genomic region is also rich in Alu repetitive sequences, frequently involved in chromosomal rearrangements.
