免疫原Full length human recombinant protein of human CAPN9(NP_006606) produced in HEK293T cell.
基因ID116694 (Rat);10753 (Human);
蛋白编码O14815
同义词GC36; nCL-4
宿主物种Mouse
抗体分型IgG1
纯化Affinity purification
储存Store at -20℃. Avoid freeze / thaw cycles.
靶点背景Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is expressed predominantly in stomach and small intestine and may have specialized functions in the digestive tract. This gene is thought to be associated with gastric cancer. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
