免疫原Human recombinant protein fragment corresponding to amino acids 1766-2144 of human MTOR(NP_004949) produced in E.coli.
基因ID56717 (Mouse);56718 (Rat);2475 (Human);
蛋白编码P42345
同义词FRAP; FRAP1; FRAP2; RAFT1; RAPT1; SKS
宿主物种Mouse
抗体分型IgG2b
纯化Affinity purification
储存Store at -20℃. Avoid freeze / thaw cycles.
靶点背景FRAP1 (mTOR) is a serine/threonine kinase that plays a critical role in cellular growth and proliferation. Perturbations in the mTOR/PI3-kinase/AKT pathway are associated with numerous forms of cancer. FRAP1 is also the target of rapamycin and its analogues, which are currently used as immunosuppressants and cancer therapeutics. Mutations affecting the gene results in Smith-Kingsmore syndrome.
推荐稀释比WB 1:2000< br/>IHC 1:150< br/>IF 1:100
产品形式Liquid
Buffer 体系PBS with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
