免疫原Full length human recombinant protein of human RAB3IP (NP_071901) produced in HEK293T cell.
基因ID29885 (Rat);216363 (Mouse);117177 (Human);
蛋白编码Q96QF0
同义词RABIN3; RABIN8
宿主物种Mouse
抗体分型IgG1
纯化Affinity purification
储存Store at -20℃. Avoid freeze / thaw cycles.
靶点背景Guanine nucleotide exchange factor (GEF) which may activate RAB8A and RAB8B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. Mediates the release of GDP from RAB8A and RAB8B but not from RAB3A or RAB5. Modulates actin organization and promotes polarized transport of RAB8A-specific vesicles to the cell surface. Together with RAB11A, RAB8A, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis.
推荐稀释比WB 1:2000< br/>IHC 1:150< br/>FLOW 1:100
产品形式Liquid
Buffer 体系PBS with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
