免疫原Recombinant Antithrombin (His33~Lys464) expressed in E.coli
基因ID462
蛋白编码P01008
同义词anti-thrombin 3; antithrombin; Antithrombin 3; Antithrombin-III; ATIII; MGC22579; serine (or cysteine) proteinase inhibitor, clade C (antithrombin), member 1; Serpin C1; serpin peptidase inhibitor clade C member 1; serpin peptidase inhibitor, clade C (antithrombin), member 1; serpin peptidase inhibitor, clade C, member 1;AI114908; At-3; AT3; AT3D; ATIII; PRO0309; SERPINC1; THPH7
宿主物种Mouse
抗体分型IgG2b Kappa
纯化Affinity purification
储存Store at -20℃. Avoid freeze / thaw cycles.
靶点背景The protein encoded by this gene is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency.
推荐稀释比WB 1:1000-1:2000 IHC-P 1:50-1:200
产品形式Liquid
Buffer 体系PBS with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
